U-ProbeAgentic Probe Design Platform

Design spatial-omics probes with configurable workflows, AI agents, and automated quality control.

🤖 AI-Guided Design

Turn natural language goals into probe design workflows with LLM-based agents.

Define MERFISH, seqFISH, RCA-based, or custom structures through declarative configs.

Run target extraction, construction, filtering, and report generation end to end.

Evaluate GC, Tm, secondary structure, off-target risk, and k-mer frequency.

Review interactive HTML and PDF reports for fast probe set comparison.

Use U-Probe through the Web UI, CLI, or Python API.

Watch three focused tutorials for the main workflow, custom probe structures, and agent interaction.

Design probes with the built-in workflow: choose genome and method, enter targets, submit tasks, and retrieve results.

Customize probe components, structure rules, and design settings for different experimental strategies.

Describe design goals in natural language, refine requests, and use AI guidance through the workflow.